About Us

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Empowering Joint Health Through Science-Driven Innovation

A clinically formulated solution for comprehensive osteoarthritis care, combining pain relief, inflammation control, and cartilage protection backed by biomedical research.

Ostizeel™ is a scientifically developed joint health formulation created to address the complex and multifactorial nature of osteoarthritis. We are a research-driven brand committed to offering a clinically proven, safe, and comprehensive solution for joint care. Our mission is to improve the quality of life for individuals affected by osteoarthritis through targeted, multi-pathway support.

Science-Led
Formulation

Developed from pain science and joint biology to precisely target nociceptive and neuropathic pain pathways in osteoarthritis.

Multi-Pathway Mechanism

Combines molecular modulation, muscle support, and cartilage protection into a unified clinical strategy for total joint health.

Clinically Researched Formulation

Developed through targeted biomedical research addressing both nociceptive and neuropathic pain with proven clinical outcomes.

Our Purpose

Osteoarthritis is a degenerative joint condition that affects millions worldwide, leading to joint pain, inflammation, and reduced mobility. It commonly impacts the knees, hips, spine, hands, and feet, and is characterized by the breakdown of cartilage, inflammation of the synovial membrane, and weakening of ligaments and muscles. Ostizeel™ has been developed as an innovative response to these challenges.

Scientific Foundation

Ostizeel™ is a synergistic formulation of Palmitoylethanolamide (PEA) and Cucumis sativus extract, designed to act on both nociceptive and neuropathic pain pathways. These two mechanisms are central to the development and persistence of osteoarthritis pain. Nociceptive pain arises from joint tissue damage and inflammation, while neuropathic pain results from nerve sensitization and neuroinflammation. By addressing both, Ostizeel™ delivers targeted and lasting relief.

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The Research Behind Ostizeel™

Backed by Research. Designed for Results.

Ostizeel™ has been scientifically formulated to modulate critical molecular mechanisms that contribute to osteoarthritis progression. It targets mast cells, TRPV1 receptors, PPAR-α, and microglial cells all of which play key roles in pain transmission and inflammation. The result is a dual-action response that reduces both inflammatory and neuropathic pain.

In addition to its analgesic action, Ostizeel™ offers chondroprotective benefits by inhibiting matrix metalloproteinases (MMPs) enzymes responsible for cartilage breakdown. The formulation also downregulates major inflammatory biomarkers such as TNF-α, IL-6, IL-1β, and NF-κB, helping reduce joint inflammation and slow disease progression.

Testimonials

After struggling with knee pain for years, I started using this supplement, and within weeks, I noticed less stiffness and much better mobility. It’s helped me get back to my daily walks without discomfort.

Pain Relief & MobilityXXXX, 58 years

This product truly supports my joints. The constant ache in my hips has diminished, and I feel more comfortable during my yoga sessions. It’s a natural way to care for my osteoarthritis.

Improved Joint ComfortYYYY 63 years

Living with osteoarthritis was limiting my activities, but since taking this supplement, I’ve experienced a significant reduction in pain and inflammation. It’s made a real difference in my day-to-day life.

Enhanced Quality of LifeAAAA, 55 years

I was hesitant to try another supplement, but this one surprised me. It’s gentle on my stomach and effective in reducing joint pain and swelling. Highly recommend for anyone with arthritis.

Gentle Yet EffectiveBBBB, 61 years

I prefer natural solutions for managing my osteoarthritis, and this product fits perfectly. My joints feel lubricated and less painful, making it easier to stay active

Natural SupportDDDD, 60 years

After several months of consistent use, my joint pain has decreased significantly. I feel stronger and more flexible, and I’m confident this nutraceutical is supporting my cartilage health.

Long-Term BenefitsHHHH, 67 years

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Clinically Validated Results

Ostizeel™ has undergone multiple clinical trials and consistently demonstrated its efficacy in improving major osteoarthritis parameters. These include enhanced scores in WOMAC, VAS, and LFI, showing improvements in pain, joint mobility, and muscle performance. The supplement has proven to be well-tolerated and safe for long-term use.

Our Global Vision

Our vision is to offer a world-class joint health solution that is accessible, effective, and built on clinical credibility. We are committed to advancing joint care science and helping individuals reclaim mobility, reduce discomfort, and improve quality of life through innovation and integrity.